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The African Coalition for Menstrual Health Management and UNFPA East and Southern Africa Regional Office, in partnership with other partners, convened the second African Symposium on Menstrual Health. The virtual symposium took place from May 25 to May 27, 2021, bringing together 717 participants from 75 countries worldwide, the majority of them from Africa. The symposium took stock of progress since the inaugural Africa Menstrual Health Symposium in 2018 and provided a platform to strengthen partnerships for advocacy and collective action and promote shared learning and innovation across Africa. The event included high-level plenary sessions, country-led sessions, and concurrent sessions. Video and artistic performances related to menstrual health in Africa were peppered throughout the symposium, adding creative flair and bringing diverse voices to the event. There was also a marketplace for organizations to share information about their programmes and activities.